KL001 [309928-48-1]

TargetMol Chemicals

KL001 [309928-48-1]

4

309928-48-1

Chemical

Research Use Only

KL001

98.85%

C21H22N2O4S

398.48

KL 001 is a Cryptochrome protein (CRY) stabilizer. KL001 prevented ubiquitin-dependent degradation of CRY, resulting in lengthening of the circadian period. KL001-mediated CRY stabilization inhibited glucagon-induced gluconeogenesis in primary hepatocytes. KL001 thus provides a tool to study the regulation of CRY-dependent physiology and aid development of clock-based therapeutics of diabetes.

3 years

CS(=O)(=O)N(CC(O)Cn1c2ccccc2c2ccccc12)Cc1ccco1

-20°C

12352200