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KLF4 antibody

GTX101509
GeneTex
ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityHuman, Mouse
TargetKLF4
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Overview

  • Supplier
    GeneTex
  • Product Name
    KLF4 antibody
  • Delivery Days Customer
    9
  • Application Supplier Note
    WB: 1:5000-1:20000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
  • Applications
    ImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Concentration
    1 mg/ml
  • Conjugate
    Unconjugated
  • Gene ID9314
  • Target name
    KLF4
  • Target description
    Kruppel like factor 4
  • Target synonyms
    endothelial Kruppel-like zinc finger protein; epithelial zinc finger protein EZF; EZF; GKLF; gut Kruppel-like factor; gut-enriched krueppel-like factor; Krueppel-like factor 4; Kruppel-like factor 4 (gut)
  • Host
    Rabbit
  • Isotype
    IgG
  • Protein IDO43474
  • Protein Name
    Krueppel-like factor 4
  • Scientific Description
    Transcription factor which acts as both an activator and repressor. Binds the CACCC core sequence. Binds to multiple sites in the 5-flanking region of its own gene and can activate its own transcription. Required for establishing the barrier function of the skin and for postnatal maturation and maintenance of the ocular surface. Involved in the differentiation of epithelial cells and may also function in skeletal and kidney development.
  • Reactivity
    Human, Mouse
  • Storage Instruction
    -20°C or -80°C,2°C to 8°C
  • UNSPSC
    12352203

References

  • 17beta-Estradiol Inhibits Proliferation and Oxidative Stress in Vascular Smooth Muscle Cells by Upregulating BHLHE40 Expression. Feng DD et al., 2021, Front Cardiovasc Med
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  • Salvia miltiorrhiza bunge exerts anti-oxidative effects through inhibiting KLF10 expression in vascular smooth muscle cells exposed to high glucose. Zhou J et al., 2020 Nov 15, J Ethnopharmacol
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  • Regulation of epidermal growth factor receptor expression and morphology of lung epithelial cells by interleukin-1beta. Nakayama I et al., 2020 Aug 1, J Biochem
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  • Kruppel-Like Factor 4 represses osteoblast differentiation via ciliary Hedgehog signaling. Takeuchi Y et al., 2018 Oct 15, Exp Cell Res
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  • Kruppel-like factor 4-dependent Staufen1-mediated mRNA decay regulates cortical neurogenesis. Moon BS et al., 2018 Jan 26, Nat Commun
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  • Cocktail of Chemical Compounds and Recombinant Proteins Robustly Promote the Stemness of Adipose-Derived Stem Cells. Guo Y et al., 2017 Dec, Cell Reprogram
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  • Involvement of CRF2 signaling in enterocyte differentiation. Ducarouge B et al., 2017 Jul 28, World J Gastroenterol
    Read more