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KML29

HY-18977
MedChem Express
CAS Number1380424-42-9
Product group Chemicals
Estimated Purity99.64
Molecular Weight549.42
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Overview

  • Supplier
    MedChem Express
  • Product Name
    KML29 [1380424-42-9]
  • Delivery Days Customer
    5
  • CAS Number
    1380424-42-9
  • Certification
    Research Use Only
  • Estimated Purity
    99.64
  • Molecular Formula
    C24H21F6NO7
  • Molecular Weight
    549.42
  • Scientific Description
    KML29 is an extremely selective, orally active and irreversible MAGL inhibitor, with IC50 values of 15 nM, 43 nM and 5.9 nM for mouse, rat and human MAGL, respectively. KML29 exhibits minimal cross-reactivity toward other central and peripheral serine hydrolases, including no detectable activity against FAAH[1][2].
  • SMILES
    O=C(N1CCC(C(C2=CC=C(OCO3)C3=C2)(C4=CC=C(OCO5)C5=C4)O)CC1)OC(C(F)(F)F)C(F)(F)F
  • Storage Instruction
    -20°C,2°C to 8°C
  • UNSPSC
    12352200

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