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KML29 [1380424-42-9]

KML29 [1380424-42-9]

T4052
TargetMol Chemicals
CAS Number1380424-42-9
DownloadMSDS
Product group Chemicals
Molecular Weight549.42
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Overview

  • Supplier
    TargetMol Chemicals
  • Product Name
    KML29 [1380424-42-9]
  • Delivery Days Customer
    9
  • CAS Number
    1380424-42-9
  • Category Supplier
    Chemical
  • Certification
    Research Use Only
  • Chemical Name
    KML29
  • Molecular Formula
    C24H21F6NO7
  • Molecular Weight
    549.42
  • Scientific Description
    KML29 is highly selective and effective monoacylglycerol lipase (MAGL) inhibitor. It has effective inhibition of human/mouse/rat MAGL (IC50: 5.9/15/43 nM). It has not inhibitory for FAAH (IC50 > 50 microM). It also effectively and selectively blocks hydrolysis of 2-arachidonoylglycerol (2-AG) in mice (IC50: 2.5 nM, 2-AG; >50 microM, AEA).
  • Shelf life instruction
    3 years
  • SMILES
    OC(C1CCN(CC1)C(=O)OC(C(F)(F)F)C(F)(F)F)(c1ccc2OCOc2c1)c1ccc2OCOc2c1
  • Storage Instruction
    -20°C
  • UNSPSC
    12352200

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