
Immunofluorescence staining of Hela cells with CSB-PA890939LA01HU at 1:133, counter-stained with DAPI. The cells were fixed in 4% formaldehyde, permeabilized using 0.2% Triton X-100 and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4°C. The secondary antibody was Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L).
KMT2B Antibody
CSB-PA890939LA01HU
ApplicationsImmunoFluorescence, ELISA
Product group Antibodies
ReactivityHuman
TargetKMT2B
Overview
- SupplierCusabio
- Product NameKMT2B Antibody
- Delivery Days Customer20
- ApplicationsImmunoFluorescence, ELISA
- CertificationResearch Use Only
- ClonalityPolyclonal
- ConjugateUnconjugated
- Gene ID9757
- Target nameKMT2B
- Target descriptionlysine methyltransferase 2B
- Target synonymsCXXC10, DYT28, HRX2, MLL1B, MLL2, MLL4, MRD68, TRX2, WBP-7, WBP7, histone-lysine N-methyltransferase 2B, WW domain binding protein 7, histone-lysine N-methyltransferase MLL4, lysine (K)-specific methyltransferase 2B, mixed lineage leukemia gene homolog 2, myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila) 4, myeloid/lymphoid or mixed-lineage leukemia protein 4, trithorax homologue 2
- HostRabbit
- IsotypeIgG
- Protein IDQ9UMN6
- Protein NameHistone-lysine N-methyltransferase 2B
- Scientific DescriptionHistone methyltransferase. Methylates Lys-4 of histone H3. H3 Lys-4 methylation represents a specific tag for epigenetic transcriptional activation. Plays a central role in beta-globin locus transcription regulation by being recruited by NFE2. Plays an important role in controlling bulk H3K4me during oocyte growth and preimplantation development. Required during the transcriptionally active period of oocyte growth for the establishment and/or maintenance of bulk H3K4 trimethylation (H3K4me3), global transcriptional silencing that preceeds resumption of meiosis, oocyte survival and normal zygotic genome activation.
- ReactivityHuman
- Storage Instruction-20°C or -80°C
- UNSPSC41116161


