Ko 143

Biorbyt

Ko 143 [461054-93-3]

10

461054-93-3

Research Use Only

C26H35N3O5

469.5732

Ko 143 is a potent and selective breast cancer resistance protein multidrug transporter (BCRP) inhibitor (EC90 = 26 nM), Ko 143 displays > 200-fold selectivity over P-gp and MRP-1 transporters.

O=C1[C@]([H])(C([H])([H])C([H])([H])C(=O)OC(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])N([H])C([C@]2([H])C([H])([H])C3C4C([H])=C([H])C(=C([H])C=4N([H])C=3[C@]([H])(C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])N21)OC([H])([H])[H])=O

12352200