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KRA-533

HY-138188
MedChem Express
CAS Number10161-87-2
DownloadMSDS
Product group Chemicals
Estimated Purity98.94
Molecular Weight314.18
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Overview

  • Supplier
    MedChem Express
  • Product Name
    KRA-533 [10161-87-2]
  • Delivery Days Customer
    10
  • CAS Number
    10161-87-2
  • Certification
    Research Use Only
  • Estimated Purity
    98.94
  • Molecular Formula
    C13H16BrNO3
  • Molecular Weight
    314.18
  • Scientific Description
    KRA-533 is a potent KRAS agonist. KRA-533 binds to the GTP/GDP binding pocket in the KRAS protein to prevent GTP cleavage, resulting in the accumulation of constitutively active GTP-bound KRAS that triggers both apoptotic and autophagic cell death pathways in cancer cells.
  • SMILES
    O=C(O)C1=CC=C(CCCCNC(CBr)=O)C=C1
  • Storage Instruction
    -20°C
  • UNSPSC
    12352200