KRA-533 [10161-87-2]

TargetMol Chemicals

KRA-533 [10161-87-2]

14

10161-87-2

Chemical

Research Use Only

KRA-533

C13H16BrNO3

314.179

KRA-533, a potent KRAS agonist, directly targets the GTP/GDP binding pocket within the KRAS protein, inhibiting GTP cleavage. This inhibition leads to the buildup of constitutively active GTP-bound KRAS, which subsequently activates both apoptotic and autophagic cell death pathways specifically in cancer cells.

3 years

OC(=O)c1ccc(CCCCNC(=O)CBr)cc1

-20°C

12352200