KU-0060648

AbMole BioScience

KU-0060648

9

881375-00-4

Chemical

Research Use Only

C33H34N4O4S

582.71

KU-0060648 is a dual inhibitor of DNA-PK and PI3Kalfa, PI3Kbèta, PI3Kdelta with IC50 of 8.6 nM and 4 nM, 0.5 nM, 0.1 nM respectively, less inhibition of PI3Kgamma with IC50 of 0.59 uM.

1-Piperazineacetamide, 4-ethyl-N-[4-[2-(4-morpholinyl)-4-oxo-4H-1-benzopyran-8-yl]-1-dibenzothienyl]-

12352200