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ProductsBack/Laduviglusib (CHIR-99021) HCl

Laduviglusib (CHIR-99021) HCl

S2924

Estimated Purity...

Product group Chemicals

Overview

Supplier
Selleck Chemicals
Product Name
Laduviglusib (CHIR-99021) HCl
Delivery Days Customer
9
Certification
Research Use Only
Estimated Purity
...
Scientific Description
Laduviglusib (CHIR-99021; CT99021) HCl is hydrochloride of CHIR-99021, which is a GSK-3alpha/beta inhibitor with IC50 of 10 nM/6.7 nM; CHIR-99021 shows greater than 500-fold selectivity for GSK-3 versus its closest homologs Cdc2 and ERK2. CHIR-99021 is a potent pharmacological activators of the Wnt/beta-catenin signaling pathway. CHIR-99021 significantly rescues light-induced autophagy and augments GR, RORalpha and autophagy-related proteins.
Storage Instruction
-80°C
UNSPSC
51202000

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