LAG3 antibody [17B4] (Azide free)
GTX33931-00
ApplicationsImmunoFluorescence, ImmunoPrecipitation, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen, Neutralisation/Blocking
Product group Antibodies
ReactivityHuman
TargetLAG3
Overview
- SupplierGeneTex
- Product NameLAG3 antibody [17B4] (Azide free)
- Delivery Days Customer9
- Antibody SpecificityRecognizes human LAG-3.
- Application Supplier NoteIHC-Fr: . *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsImmunoFluorescence, ImmunoPrecipitation, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen, Neutralisation/Blocking
- CertificationResearch Use Only
- ClonalityMonoclonal
- Clone ID17B4
- Concentration1 mg/ml
- ConjugateUnconjugated
- Gene ID3902
- Target nameLAG3
- Target descriptionlymphocyte activating 3
- Target synonymsCD223; lymphocyte activation gene 3 protein; lymphocyte-activation gene 3
- HostMouse
- IsotypeIgG1
- Protein IDP18627
- Protein NameLymphocyte activation gene 3 protein
- Scientific DescriptionLymphocyte-activation protein 3 belongs to Ig superfamily and contains 4 extracellular Ig-like domains. The LAG3 gene contains 8 exons. The sequence data, exon/intron organization, and chromosomal localization all indicate a close relationship of LAG3 to CD4. [provided by RefSeq, Jul 2008]
- ReactivityHuman
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203
References
- Human lymphocyte activation gene-3 molecules expressed by activated T cells deliver costimulation signal for dendritic cell activation. Casati C et al., 2008 Mar 15, J ImmunolRead more
- A soluble lymphocyte activation gene-3 (sLAG-3) protein as a prognostic factor in human breast cancer expressing estrogen or progesterone receptors. Triebel F et al., 2006 Apr 8, Cancer LettRead more
- The negative regulatory function of the lymphocyte-activation gene-3 co-receptor (CD223) on human T cells. Macon-Lemaitre L et al., 2005 Jun, ImmunologyRead more
- Immunological mechanisms elicited at the tumour site by lymphocyte activation gene-3 (LAG-3) versus IL-12: sharing a common Th1 anti-tumour immune pathway. Di Carlo E et al., 2005 Jan, J PatholRead more
- T Lymphocytes infiltrating various tumour types express the MHC class II ligand lymphocyte activation gene-3 (LAG-3): role of LAG-3/MHC class II interactions in cell-cell contacts. Demeure CE et al., 2001 Sep, Eur J CancerRead more
- CD3/TCR complex-associated lymphocyte activation gene-3 molecules inhibit CD3/TCR signaling. Hannier S et al., 1998 Oct 15, J ImmunolRead more
- Characterization of the major histocompatibility complex class II binding site on LAG-3 protein. Huard B et al., 1997 May 27, Proc Natl Acad Sci U S ARead more
- Cellular expression and tissue distribution of the human LAG-3-encoded protein, an MHC class II ligand. Huard B et al., 1994, ImmunogeneticsRead more
- Characterization of the lymphocyte activation gene 3-encoded protein. A new ligand for human leukocyte antigen class II antigens. Baixeras E et al., 1992 Aug 1, J Exp MedRead more