LAIR1 antibody [NKTA255] (PerCP-Cy5.5)
GTX00485-11
Overview
- SupplierGeneTex
- Product NameLAIR1 antibody [NKTA255] (PerCP-Cy5.5)
- Delivery Days Customer9
- Application Supplier NoteFACS: 4 microl reagent / 100 microl of whole blood or 106 cells in a suspension. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsFlow Cytometry
- CertificationResearch Use Only
- ClonalityMonoclonal
- Clone IDNKTA255
- ConjugateDouble Conjugated
- FormulationLiquid
- Gene ID3903
- Target nameLAIR1
- Target descriptionleukocyte associated immunoglobulin like receptor 1
- Target synonymsCD305; immunoglobulin heavy chain variable region; LAIR-1; leukocyte-associated Ig-like receptor 1; leukocyte-associated immunoglobulin-like receptor 1
- HostMouse
- IsotypeIgG1
- Protein IDQ6GTX8
- Protein NameLeukocyte-associated immunoglobulin-like receptor 1
- Scientific DescriptionThe protein encoded by this gene is an inhibitory receptor found on peripheral mononuclear cells, including natural killer cells, T cells, and B cells. Inhibitory receptors regulate the immune response to prevent lysis of cells recognized as self. The gene is a member of both the immunoglobulin superfamily and the leukocyte-associated inhibitory receptor family. The gene maps to a region of 19q13.4 called the leukocyte receptor cluster, which contains at least 29 genes encoding leukocyte-expressed receptors of the immunoglobulin superfamily. The encoded protein has been identified as an anchor for tyrosine phosphatase SHP-1, and may induce cell death in myeloid leukemias. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2014]
- ReactivityHuman
- Storage Instruction2°C to 8°C
- UNSPSC12352203