LAIR1 antibody [NKTA255]

GeneTex

LAIR1 antibody [NKTA255]

9

Flow Cytometry, ImmunoPrecipitation, Western Blot

Research Use Only

Monoclonal

NKTA255

1 mg/ml

Unconjugated

LAIR1

leukocyte associated immunoglobulin like receptor 1

CD305; immunoglobulin heavy chain variable region; LAIR-1; leukocyte-associated Ig-like receptor 1; leukocyte-associated immunoglobulin-like receptor 1

Mouse

IgG1

The protein encoded by this gene is an inhibitory receptor found on peripheral mononuclear cells, including natural killer cells, T cells, and B cells. Inhibitory receptors regulate the immune response to prevent lysis of cells recognized as self. The gene is a member of both the immunoglobulin superfamily and the leukocyte-associated inhibitory receptor family. The gene maps to a region of 19q13.4 called the leukocyte receptor cluster, which contains at least 29 genes encoding leukocyte-expressed receptors of the immunoglobulin superfamily. The encoded protein has been identified as an anchor for tyrosine phosphatase SHP-1, and may induce cell death in myeloid leukemias. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2014]

Human

2°C to 8°C

12352203