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LAMP2 antibody

GTX103214
GeneTex
ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
TargetLAMP2
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Overview

  • Supplier
    GeneTex
  • Product Name
    LAMP2 antibody
  • Delivery Days Customer
    9
  • Application Supplier Note
    WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
  • Applications
    ImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Concentration
    0.42 mg/ml
  • Conjugate
    Unconjugated
  • Gene ID3920
  • Target name
    LAMP2
  • Target description
    lysosomal associated membrane protein 2
  • Target synonyms
    CD107b, DND, LAMP-2, LAMPB, LGP-96, LGP110, lysosome-associated membrane glycoprotein 2, CD107 antigen-like family member B
  • Host
    Rabbit
  • Isotype
    IgG
  • Protein IDP13473
  • Protein Name
    Lysosome-associated membrane glycoprotein 2
  • Scientific Description
    The protein encoded by this gene is a member of a family of membrane glycoproteins. This glycoprotein provides selectins with carbohydrate ligands. It may play a role in tumor cell metastasis. It may also function in the protection, maintenance, and adhesion of the lysosome. Alternative splicing of this gene results in multiple transcript variants encoding distinct proteins. [provided by RefSeq]
  • Storage Instruction
    -20°C or -80°C,2°C to 8°C
  • UNSPSC
    12352203

References

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  • Chen JC, Hsieh YY, Lo HL, et al. In Vitro and In Silico Mechanistic Insights into miR-21-5p-Mediated Topoisomerase Drug Resistance in Human Colorectal Cancer Cells. Biomolecules. 2019,9(9). doi: 10.3390/biom9090467
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  • Izumi H, Li Y, Shibaki M, et al. Recycling endosomal CD133 functions as an inhibitor of autophagy at the pericentrosomal region. Sci Rep. 2019,9(1):2236. doi: 10.1038/s41598-019-39229-8
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  • Kuo WY, Lin JJ, Hsu HJ, et al. Noninvasive assessment of characteristics of novel anti-HER2 antibodies by molecular imaging in a human gastric cancer xenograft-bearing mouse model. Sci Rep. 2018,8(1):13735. doi: 10.1038/s41598-018-32094-x
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  • Lai MC, Chang CM, Sun HS. Hypoxia Induces Autophagy through Translational Up-Regulation of Lysosomal Proteins in Human Colon Cancer Cells. PLoS One. 2016,11(4):e0153627. doi: 10.1371/journal.pone.0153627
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  • Lai CY, Yeh DW, Lu CH, et al. Identification of Thiostrepton as a Novel Inhibitor for Psoriasis-like Inflammation Induced by TLR7-9. J Immunol. 2015,195(8):3912-21. doi: 10.4049/jimmunol.1500194
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  • Hung TM, Yuan RH, Huang WP, et al. Increased Autophagy Markers Are Associated with Ductular Reaction during the Development of Cirrhosis. Am J Pathol. 2015,185(9):2454-67. doi: 10.1016/j.ajpath.2015.05.010
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  • Liu TP, Lo HL, Wei LS, et al. S-Adenosyl-L-methionine-competitive inhibitors of the histone methyltransferase EZH2 induce autophagy and enhance drug sensitivity in cancer cells. Anticancer Drugs. 2015,26(2):139-47. doi: 10.1097/CAD.0000000000000166
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