LARGE antibody

GeneTex

LARGE antibody

9

WB: 1:500-1:3000. IHC-P: 1:100-1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

Western Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin

Research Use Only

Polyclonal

1 mg/ml

Unconjugated

LARGE1

LARGE xylosyl- and glucuronyltransferase 1

LARGE, MDC1D, MDDGA6, MDDGB6, xylosyl- and glucuronyltransferase LARGE1, acetylglucosaminyltransferase-like 1A, acetylglucosaminyltransferase-like protein, glycosyltransferase-like protein LARGE1

Rabbit

IgG

Xylosyl- and glucuronyltransferase LARGE1

This gene, which is one of the largest in the human genome, encodes a member of the N-acetylglucosaminyltransferase gene family. It encodes a glycosyltransferase which participates in glycosylation of alpha-dystroglycan, and may carry out the synthesis of glycoprotein and glycosphingolipid sugar chains. It may also be involved in the addition of a repeated disaccharide unit. Mutations in this gene cause MDC1D, a novel form of congenital muscular dystrophy with severe mental retardation and abnormal glycosylation of alpha-dystroglycan. Alternative splicing of this gene results in two transcript variants that encode the same protein. [provided by RefSeq]

Human, Mouse, Rat

-20°C or -80°C,2°C to 8°C

12352203