Lariatin A [732286-09-8]

TargetMol Chemicals

Lariatin A [732286-09-8]

44

732286-09-8

Chemical

Research Use Only

Lariatin A

C94H143N27O25

2051.342

Lariatin A is an antimycobacterial lasso peptide originally isolated from R. jostii. It is active against M. tuberculosis and M. smegmatis in vitro (MICs = 0.39 and 0.1 microg/ml, respectively). Lariatin A increases survival in a silkworm model of M. smegmatis infection (ED50 = 0.5 microg/g).

3 years

CC[C@H](C)[C@H](NC(=O)[C@@H](NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CO)NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)CNC(=O)[C@@H](NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@@H]1CCC(=O)NCC(=O)N[C@@H](CO)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CC(C)C)C(=O)NC(C(C)C)C(=O)N[C@@H](Cc2ccc(O)cc2)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N1)C(C)C)C(C)C)C(=O)N[C@@H](CCCCN)C(=O)N1CCC[C@H]1C(O)=O - @:92,@@:124 -

-20°C

12352200