Chemical Structure
Chemical Structure
Lariatin A [732286-09-8]
AG-CN2-0120
Overview
- SupplierAdipoGen Life Sciences
- Product NameLariatin A
- Delivery Days Customer10
- CAS Number732286-09-8
- CertificationResearch Use Only
- Estimated Purity>95%
- Hazard InformationWarning
- Molecular FormulaC94H143N27O25
- Molecular Weight2051.4
- Scientific DescriptionChemical. CAS: 732286-09-8. Formula: C94H143N27O25. MW: 2051.4. Isolated from Rhodococcus jostii. Peptide with lasso structure. Antimycobacterial. - Peptide with lasso structure. Antimycobacterial.
- SMILES[H]N([C@@H](CC1=CNC2=C1C=CC=C2)C(=O)N[C@@H](C(C)C)C(=O)NCC(=O)N[C@@H](CC1=CN=CN1)C(=O)N[C@@H](CO)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CCCCN)C(=O)N1CCC[C@H]1C(O)=O)C(=O)C1CCC(=O)N([H])CC(=O)N[C@@H](CO)C(=O)N[C@@H](CCC(N)=O)C(=O)N([H])[C@@H](CC(C)C)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CC2=CC=C(O)C=C2)C(=O)N[C@H](CCCNC(N)=N)C(=O)N1
- Storage Instruction-20°C,2°C to 8°C
- UNSPSC12352200
References
- Lariatins, antimycobacterial peptides produced by Rhodococcus sp. K01-B0171, have a lasso structure: M. Iwatsuki, et al.; JACS 128, 7486 (2006)
- Lariatins, novel anti-mycobacterial peptides with a lasso structure, produced by Rhodococcus jostii K01-B0171: M. Iwatsuki, et al.; J. Antibiot. (Tokyo) 60, 357 (2007)
- Lys17 in the 'lasso' peptide lariatin A is responsible for anti-mycobacterial activity: M. Iwatsuki, et al.; Bioorg. Med. Chem. Lett. 19, 2888 (2009)
- Molecular cloning of the gene cluster for lariatin biosynthesis of Rhodococcus jostii K01-B0171: J. Inokoshi, et al.; Appl. Microbiol. Biotechnol. 95, 451 (2012)