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Larotrectinib

HY-12866
MedChem Express
CAS Number1223403-58-4
DownloadMSDS
Product group Chemicals
Estimated Purity99.95
Molecular Weight428.44
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Overview

  • Supplier
    MedChem Express
  • Product Name
    Larotrectinib [1223403-58-4]
  • Delivery Days Customer
    10
  • CAS Number
    1223403-58-4
  • Certification
    Research Use Only
  • Estimated Purity
    99.95
  • Molecular Formula
    C21H22F2N6O2
  • Molecular Weight
    428.44
  • Scientific Description
    Larotrectinib (LOXO-101) is an ATP-competitive oral, selective inhibitor of the tropomyosin-related kinase (TRK) family receptors, with low nanomolar 50% inhibitory concentrations against all three isoforms (TRKA, B, and C).
  • SMILES
    O=C(N1C[C@@H](O)CC1)NC2=C3N=C(N4[C@@H](C5=CC(F)=CC=C5F)CCC4)C=CN3N=C2
  • Storage Instruction
    -20°C,2°C to 8°C
  • UNSPSC
    12352200