WB analysis of PMA-treated HeLa (A), CD3-treated Jurkat (B), PMA-treated Raw264.7 (C), PMA-treated PC12 (D) whole cell lysates using GTX32291 LAT (phospho Tyr191) antibody.
WB analysis of PMA-treated HeLa (A), CD3-treated Jurkat (B), PMA-treated Raw264.7 (C), PMA-treated PC12 (D) whole cell lysates using GTX32291 LAT (phospho Tyr191) antibody.
LAT (phospho Tyr191) antibody
GTX32291
ApplicationsWestern Blot
Product group Antibodies
ReactivityHuman, Mouse, Rat
TargetLAT
Overview
- SupplierGeneTex
- Product NameLAT (phospho Tyr191) antibody
- Delivery Days Customer9
- Application Supplier NoteWB: 1:500 - 1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsWestern Blot
- CertificationResearch Use Only
- ClonalityPolyclonal
- ConjugateUnconjugated
- Gene ID27040
- Target nameLAT
- Target descriptionlinker for activation of T cells
- Target synonyms36 kDa phospho-tyrosine adapter protein; 36 kDa phospho-tyrosine adaptor protein; IMD52; LAT1; linker for activation of T cells, transmembrane adaptor; linker for activation of T-cells family member 1; p36-38; pp36
- HostRabbit
- IsotypeIgG
- Protein IDO43561
- Protein NameLinker for activation of T-cells family member 1
- Scientific DescriptionThe protein encoded by this gene is phosphorylated by ZAP-70/Syk protein tyrosine kinases following activation of the T-cell antigen receptor (TCR) signal transduction pathway. This transmembrane protein localizes to lipid rafts and acts as a docking site for SH2 domain-containing proteins. Upon phosphorylation, this protein recruits multiple adaptor proteins and downstream signaling molecules into multimolecular signaling complexes located near the site of TCR engagement. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]
- ReactivityHuman, Mouse, Rat
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203