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ProductsBack/LATS2 Polyclonal Antibody

Immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using LATS2 Polyclonal Antibody at dilution 1:30

Immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using LATS2 Polyclonal Antibody at dilution 1:30

Immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using LATS2 Polyclonal Antibody at dilution 1:30

LATS2 Polyclonal Antibody

E-AB-15942

Product group Antibodies

Overview

Supplier
Elabscience
Product Name
LATS2 Polyclonal Antibody
Delivery Days Customer
12
Applications Supplier
ELISA IHC
Certification
Research Use Only
Concentration
0.5mg/ml
Scientific Description
This gene encodes a serine/threonine protein kinase belonging to the LATS tumor suppressor family. The protein localizes to centrosomes during interphase, and early and late metaphase. It interacts with the centrosomal proteins aurora-A and ajuba and is required for accumulation of gamma-tubulin and spindle formation at the onset of mitosis. It also interacts with a negative regulator of p53 and may function in a positive feedback loop with p53 that responds to cytoskeleton damage. Additionally, it can function as a co-repressor of androgen-responsive gene expression.
UNSPSC
12352203

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