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FACS analysis of MCF-7 cells using GTX80914 LDL Receptor antibody, Internal. Top histogram : negative control Bottom histogram : MCF-7 cells
FACS analysis of MCF-7 cells using GTX80914 LDL Receptor antibody, Internal. Top histogram : negative control Bottom histogram : MCF-7 cells
FACS analysis of MCF-7 cells using GTX80914 LDL Receptor antibody, Internal. Top histogram : negative control Bottom histogram : MCF-7 cells

LDL Receptor antibody, Internal

GTX80914
GeneTex
ApplicationsFlow Cytometry, Western Blot
DownloadDatasheet
Product group Antibodies
TargetLDLR
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Overview

  • Supplier
    GeneTex
  • Product Name
    LDL Receptor antibody, Internal
  • Delivery Days Customer
    9
  • Application Supplier Note
    WB: 1:1000. FACS: 1:10-1:50. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
  • Applications
    Flow Cytometry, Western Blot
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Conjugate
    Unconjugated
  • Gene ID3949
  • Target name
    LDLR
  • Target description
    low density lipoprotein receptor
  • Target synonyms
    FH; FHC; FHCL1; LDL receptor; LDLCQ2; low-density lipoprotein receptor; low-density lipoprotein receptor class A domain-containing protein 3
  • Host
    Rabbit
  • Isotype
    IgG
  • Protein IDP01130
  • Protein Name
    Low-density lipoprotein receptor
  • Scientific Description
    The low density lipoprotein receptor (LDLR) gene family consists of cell surface proteins involved in receptor-mediated endocytosis of specific ligands. Low density lipoprotein (LDL) is normally bound at the cell membrane and taken into the cell ending up in lysosomes where the protein is degraded and the cholesterol is made available for repression of microsomal enzyme 3-hydroxy-3-methylglutaryl coenzyme A (HMG CoA) reductase, the rate-limiting step in cholesterol synthesis. At the same time, a reciprocal stimulation of cholesterol ester synthesis takes place. Mutations in this gene cause the autosomal dominant disorder, familial hypercholesterolemia. Alternate splicing results in multiple transcript variants.[provided by RefSeq, Sep 2010]
  • Storage Instruction
    -20°C or -80°C,2°C to 8°C
  • UNSPSC
    12352203

References

  • Lipoprotein(a) catabolism is regulated by proprotein convertase subtilisin/kexin type 9 through the low density lipoprotein receptor. Romagnuolo R et al., 2015 May 1, J Biol Chem
    Read more

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