LDN-193189 (dihydrochloride)

MedChem Express

LDN-193189 (dihydrochloride) [1435934-00-1]

14

1435934-00-1

Research Use Only

99.75

C25H24Cl2N6

479.40

LDN-193189 (dihydrochloride) is a potent selective BMP type I receptor (BMP I) inhibitor. LDN-193189 efficiently inhibits transcriptional activity of the BMP type I receptors ALK2 and ALK3 with IC 50 values of 5 nM and 30 nM, respectively. LDN-193189 can be used for the research of bone morphogenetic protein signalling, such as fibrodysplasia ossificans progressiva [1] [2] [3] .

C1(C2=C3N=CC(C4=CC=C(N5CCNCC5)C=C4)=CN3N=C2)=CC=NC6=CC=CC=C16.Cl.Cl

2°C to 8°C

12352200