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LDN-193189 dihydrochloride

M2805
AbMole BioScience
CAS Number1435934-00-1
Product group Chemicals
Estimated Purity1
Molecular Weight479.40
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Overview

  • Supplier
    AbMole BioScience
  • Product Name
    LDN-193189 dihydrochloride
  • Delivery Days Customer
    9
  • CAS Number
    1435934-00-1
  • Category Supplier
    Chemical
  • Certification
    Research Use Only
  • Estimated Purity
    1
  • Molecular Formula
    C25H24Cl2N6
  • Molecular Weight
    479.40
  • Scientific Description
    LDN-193189 dihydrochloride is a selective BMP signaling inhibitor, and inhibits the transcriptional activity of the BMP type I receptors ALK2 and ALK3 with IC50 of 5 nM and 30 nM, respectively, 200-fold selectivity for BMP versus TGF-bèta.
  • SMILES
    Cl.C1CN(CCN1)C2=CC=C(C=C2)C3=C[N]4N=CC(=C4N=C3)C5=CC=NC6=C5C=CC=C6
  • Storage Instruction
    4°C, dry, sealed
  • UNSPSC
    12352200