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ProductsBack/LDN-211904 (oxalate)

LDN-211904 (oxalate)

HY-107460
MedChem Express
CAS Number1198408-78-4
DownloadMSDS
Product group Chemicals
Estimated Purity99.0
Molecular Weight444.87
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Overview

  • Supplier
    MedChem Express
  • Product Name
    LDN-211904 (oxalate) [1198408-78-4]
  • Delivery Days Customer
    10
  • CAS Number
    1198408-78-4
  • Certification
    Research Use Only
  • Estimated Purity
    99.0
  • Molecular Formula
    C21H21ClN4O5
  • Molecular Weight
    444.87
  • Scientific Description
    LDN-211904 oxalate (compound 32) is a potent and selective EphB3 inhibitor with an IC 50 of 0.079 microM. LDN-211904 oxalate shows good metabolic stability in mouse liver microsomes. LDN-211904 oxalate with cetuximab could be effective in inhibiting STAT3-activated CSC stemness and cetuximab resistance in CRC [1] [2] .
  • SMILES
    O=C(C(O)=O)O.O=C(C1=CN=C2C=CC(C3CCNCC3)=CN21)NC4=C(Cl)C=CC=C4
  • Storage Instruction
    -20°C
  • UNSPSC
    12352200