LDN-211904 oxalate [1198408-78-4]

TargetMol Chemicals

LDN-211904 oxalate [1198408-78-4]

44

1198408-78-4

Chemical

Research Use Only

LDN-211904

C21H21ClN4O5

444.87

LDN-211904 oxalate (compound 32), a potent and selective EphB3 inhibitor, demonstrates an IC50 of 0.079 microM and shows good metabolic stability in mouse liver microsomes. When combined with cetuximab, it may effectively inhibit STAT3-activated CSC stemness and cetuximab resistance in CRC [1] [2].

3 years

OC(=O)C(O)=O.Clc1ccccc1NC(=O)c1cnc2ccc(cn12)C1CCNCC1

-20°C

12352200