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LE135 [155877-83-1]

LE135 [155877-83-1]

T22920
TargetMol Chemicals
CAS Number155877-83-1
Product group Chemicals
Estimated Purity98.33%
Molecular Weight438.56
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Overview

  • Supplier
    TargetMol Chemicals
  • Product Name
    LE135 [155877-83-1]
  • Delivery Days Customer
    4
  • CAS Number
    155877-83-1
  • Category Supplier
    Chemical
  • Certification
    Research Use Only
  • Chemical Name
    LE135
  • Estimated Purity
    98.33%
  • Molecular Formula
    C29H30N2O2
  • Molecular Weight
    438.56
  • Scientific Description
    LE135 is a potent RAR antagonist that binds selectively to RARalpha (Ki of 1.4 microM) and RARbeta (Ki of 220 nM), showing higher affinity for RARbeta. It is highly selective over RARgamma, RXRalpha, RXRbeta, and RXRgamma. LE135 also acts as a potent TRPV1 and TRPA1 receptor activator with EC50s of 2.5 microM and 20 microM, respectively.
  • Shelf life instruction
    3 years
  • SMILES
    CN1c2cc3c(cc2N=C(c2ccc(cc2)C(O)=O)c2ccccc12)C(C)(C)CCC3(C)C
  • Storage Instruction
    -20°C
  • UNSPSC
    12352200

MSDS

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