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LEF1 antibody

GTX129186
GeneTex
ApplicationsWestern Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
DownloadDatasheet
Product group Antibodies
ReactivityHuman, Rat
TargetLEF1
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Overview

  • Supplier
    GeneTex
  • Product Name
    LEF1 antibody
  • Delivery Days Customer
    9
  • Antibody Specificity
    Knockdown/Knockout validation was supported by references (PMID:35801925)
  • Application Supplier Note
    WB: 1:500-1:3000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
  • Applications
    Western Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Concentration
    1 mg/ml
  • Conjugate
    Unconjugated
  • Gene ID51176
  • Target name
    LEF1
  • Target description
    lymphoid enhancer binding factor 1
  • Target synonyms
    LEF-1; lymphoid enhancer-binding factor 1; T cell-specific transcription factor 1-alpha; TCF10; TCF1ALPHA; TCF1-alpha; TCF7L3
  • Host
    Rabbit
  • Isotype
    IgG
  • Protein IDQ9UJU2
  • Protein Name
    Lymphoid enhancer-binding factor 1
  • Scientific Description
    LEF1 is a nuclear protein that is expressed in pre-B and T cells. It binds to a functionally important site in the T-cell receptor-alpha (TCRA; MIM 186880) enhancer and confers maximal enhancer activity. LEF1 belongs to a family of regulatory proteins that share homology with high mobility group protein-1 (HMG1; MIM 163905) (Waterman et al., 1991 [PubMed 2010090]; van Genderen et al., 1994 [PubMed 7958926]).[supplied by OMIM]
  • Reactivity
    Human, Rat
  • Storage Instruction
    -20°C or -80°C,2°C to 8°C
  • UNSPSC
    12352203

References

  • DBC1 is a key positive regulator of enhancer epigenomic writers KMT2D and p300.
    Read more
  • MiR-378a-3p as a putative biomarker for hepatocellular carcinoma diagnosis and prognosis: Computational screening with experimental validation. Qian F et al., 2021 Feb, Clin Transl Med
    Read more
  • Obatoclax, a Pan-BCL-2 Inhibitor, Downregulates Survivin to Induce Apoptosis in Human Colorectal Carcinoma Cells Via Suppressing WNT/beta-catenin Signaling. Or CR et al., 2020 Mar 5, Int J Mol Sci
    Read more
  • Lactoferrin promotes hair growth in mice and increases dermal papilla cell proliferation through Erk/Akt and Wnt signaling pathways. Huang HC et al., 2019 Jul, Arch Dermatol Res
    Read more
  • TOP2A induces malignant character of pancreatic cancer through activating beta-catenin signaling pathway. Pei YF et al., 2018 Jan, Biochim Biophys Acta Mol Basis Dis
    Read more