LEF1 antibody [1C3.1D10]

GeneTex

LEF1 antibody [1C3.1D10]

9

Recognizes all human LEF1 isoforms using Western blotting. The antibody does not cross-react with TCF1 or TCF4.

WB: Use at a concentration of 1 - 5 microg/ml. Predicted MW 55-57 kDa. Optimal dilutions/concentrations should be determined by the end user.

Western Blot

Research Use Only

Monoclonal

1C3.1D10

1 mg/ml

Unconjugated

LEF1

lymphoid enhancer binding factor 1

LEF-1; lymphoid enhancer-binding factor 1; T cell-specific transcription factor 1-alpha; TCF10; TCF1ALPHA; TCF1-alpha; TCF7L3

Mouse

IgG1

Lymphoid enhancer-binding factor 1

This gene encodes a transcription factor belonging to a family of proteins that share homology with the high mobility group protein-1. The protein encoded by this gene can bind to a functionally important site in the T-cell receptor-alpha enhancer, thereby conferring maximal enhancer activity. This transcription factor is involved in the Wnt signaling pathway, and it may function in hair cell differentiation and follicle morphogenesis. Mutations in this gene have been found in somatic sebaceous tumors. This gene has also been linked to other cancers, including androgen-independent prostate cancer. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2009]

Human

-20°C or -80°C,2°C to 8°C

12352203