Lenalidomide (CC-5013) [191732-72-6]
S1029
Product group Chemicals
Overview
- SupplierSelleck Chemicals
- Product NameLenalidomide (CC-5013) [191732-72-6]
- Delivery Days Customer9
- CertificationResearch Use Only
- Scientific DescriptionLenalidomide (CC-5013) is a TNF-alfa secretion inhibitor with IC50 of 13 nM in PBMCs. Lenalidomide (CC-5013) is a ligand of ubiquitin E3 ligase cereblon (CRBN), and it causes selective ubiquitination and degradation of two lymphoid transcription factors, IKZF1 and IKZF3, by the CRBN-CRL4 ubiquitin ligase. Lenalidomide promotes cleaved caspase-3 expression and inhibit VEGF expression and induces apoptosis.
- UNSPSC12352200
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![Lenalidomide [191732-72-6]](https://www.targetmol.com/group3/M00/02/65/CgoaEWY7LLOEK8mHAAAAAPLCgS0684.png)
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Molecular Weight259.26
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