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Lenalidomide (hydrochloride)

HY-A0003A
MedChem Express
CAS Number1243329-97-6
DownloadMSDS
Product group Chemicals
Molecular Weight295.72
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Overview

  • Supplier
    MedChem Express
  • Product Name
    Lenalidomide (hydrochloride) [1243329-97-6]
  • Delivery Days Customer
    10
  • CAS Number
    1243329-97-6
  • Certification
    Research Use Only
  • Molecular Formula
    C13H14ClN3O3
  • Molecular Weight
    295.72
  • Scientific Description
    Lenalidomide hydrochloride (CC-5013 hydrochloride), a derivative of Thalidomide, acts as molecular glue. Lenalidomide hydrochloride is an orally active immunomodulator. Lenalidomide hydrochloride (CC-5013 hydrochloride) is a ligand of ubiquitin E3 ligase cereblon (CRBN), and it causes selective ubiquitination and degradation of two lymphoid transcription factors, IKZF1 and IKZF3, by the CRBN-CRL4 ubiquitin ligase. Lenalidomide hydrochloride (CC-5013 hydrochloride) specifically inhibits growth of mature B-cell lymphomas, including multiple myeloma, and induces IL-2 release from T cells[1][2].
  • SMILES
    O=C1C2=CC=CC(N)=C2CN1C(C(N3)=O)CCC3=O.[H]Cl
  • UNSPSC
    12352200

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