Lenalidomide hydrochloride [1243329-97-6]

TargetMol Chemicals

Lenalidomide hydrochloride [1243329-97-6]

72

1243329-97-6

Chemical

Research Use Only

Lenalidomide hydrochloride

C13H14ClN3O3

295.72

Lenalidomide hydrochloride (CC-5013 hydrochloride), a Thalidomide derivative, functions as molecular glue and serves as an orally active immunomodulator. As a ligand for the ubiquitin E3 ligase cereblon (CRBN), it facilitates the selective ubiquitination and degradation of the lymphoid transcription factors IKZF1 and IKZF3 through the CRBN-CRL4 ubiquitin ligase. Specifically, Lenalidomide hydrochloride inhibits the growth of mature B-cell lymphomas, including multiple myeloma, and promotes IL-2 release from T cells [1] [2].

3 years

Cl.O=C1NC(=O)C(N2C(=O)C=3C=CC=C(N)C3C2)CC1

-20°C

12352200