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Leriglitazone

ORB1989209
Biorbyt
CAS Number146062-44-4
Product group Chemicals
Estimated Purity98.00%
Molecular Weight372.44
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Overview

  • Supplier
    Biorbyt
  • Product Name
    Leriglitazone [146062-44-4]
  • Delivery Days Customer
    10
  • CAS Number
    146062-44-4
  • Certification
    Research Use Only
  • Estimated Purity
    98.00%
  • Molecular Formula
    C19H20N2O4S
  • Molecular Weight
    372.44
  • Scientific Description
    Leriglitazone, a metabolite of pioglitazone, binds to the PPARgamma C-terminal ligand-binding domain (Ki: 1.2 microM) and induces transcriptional efficacy of the PPARgamma (EC50: 680 nM). Leriglitazone PioOH is a PPARgamma agonist, stabilizes the PPARgamma activation function-2 (AF-2) co-activator binding surface.
  • SMILES
    O=C1SC(C(=O)N1)CC2=CC=C(OCCC3=NC=C(C=C3)C(O)C)C=C2
  • Storage Instruction
    -20°C
  • UNSPSC
    12352200

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