Leriglitazone [146062-44-4]

TargetMol Chemicals

Leriglitazone [146062-44-4]

44

146062-44-4

Chemical

Research Use Only

Leriglitazone

C19H20N2O4S

372.44

Leriglitazone, a metabolite of pioglitazone, binds to the PPARgamma C-terminal ligand-binding domain (Ki: 1.2 microM) and induces transcriptional efficacy of the PPARgamma (EC50: 680 nM). Leriglitazone PioOH is a PPARgamma agonist, stabilizes the PPARgamma activation function-2 (AF-2) co-activator binding surface.

3 years

O=C1SC(C(=O)N1)CC2=CC=C(OCCC3=NC=C(C=C3)C(O)C)C=C2

-20°C

12352200