LGX818

AbMole BioScience

LGX818

9

1269440-17-6

Chemical

Research Use Only

C22H27ClFN7O4S

540.01

LGX818 is a highly potent RAF inhibitor with selective anti-proliferative and apoptotic activity in cells expressing B-RAF(V600E) with EC50 of 4 nM.

COC(=O)NC(C)CNC1=NC=CC(=N1)C2=C[N](N=C2C3=C(F)C(=CC(=C3)Cl)N[S;v6](C)(=O)=O)C(C)C

12352200