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Lifitegrast

HY-19344
MedChem Express
CAS Number1025967-78-5
Product group Chemicals
Estimated Purity99.29
Molecular Weight615.48
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Overview

  • Supplier
    MedChem Express
  • Product Name
    Lifitegrast [1025967-78-5]
  • Delivery Days Customer
    5
  • CAS Number
    1025967-78-5
  • Certification
    Research Use Only
  • Estimated Purity
    99.29
  • Molecular Formula
    C29H24Cl2N2O7S
  • Molecular Weight
    615.48
  • Scientific Description
    Lifitegrast (SAR 1118) is a potent integrin antagonist. Lifitegrast blocks the binding of intercellular adhesion molecule 1 (ICAM-1) to lymphocyte function-associated antigen 1 (LFA-1), interrupting the T cell-mediated inflammatory cycle. Lifitegrast inhibits Jurkat T cell attachment to ICAM-1 with an IC50 of 2.98 nM. Lifitegrast can be used for researching dry eye disease[1].
  • SMILES
    O=C(O)[C@H](CC1=CC=CC(S(=O)(C)=O)=C1)NC(C2=C(Cl)C3=C(CN(C(C4=CC=C5C=COC5=C4)=O)CC3)C=C2Cl)=O
  • Storage Instruction
    -20°C,2°C to 8°C
  • UNSPSC
    12352200

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