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Lifitegrast

M5852
AbMole BioScience
CAS Number1025967-78-5
Product group Chemicals
Estimated Purity0.9981
Molecular Weight615.48
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Overview

  • Supplier
    AbMole BioScience
  • Product Name
    Lifitegrast
  • Delivery Days Customer
    9
  • CAS Number
    1025967-78-5
  • Category Supplier
    Chemical
  • Certification
    Research Use Only
  • Estimated Purity
    0.9981
  • Molecular Formula
    C29H24Cl2N2O7S
  • Molecular Weight
    615.48
  • Scientific Description
    Lifitegrast is an antagonist of integrin lymphocyte function associated antigen-1 (LFA-1). The IC50 of Jurkat T cells to icAM-1 was 2.98nM. Lifitegrast blocks the interaction between LFA-1 and ICAM-1, thereby reducing T cell activity and cytokine secretion.
  • SMILES
    C[S](=O)(=O)C1=CC=CC(=C1)CC(NC(=O)C2=C(Cl)C=C3CN(CCC3=C2Cl)C(=O)C4=CC=C5C=COC5=C4)C(O)=O
  • UNSPSC
    12352200

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