IHC-P analysis of human ovary adenocarcinoma tissue using GTX84216 LIN7B antibody [1C9]. Antigen retrieval : Heat-induced epitope retrieval by 10mM citrate buffer, pH6.0, 100oC for 10min. Dilution : 1:50
![IHC-P analysis of human bladder carcinoma tissue using GTX84216 LIN7B antibody [1C9]. Antigen retrieval : Heat-induced epitope retrieval by 10mM citrate buffer, pH6.0, 100oC for 10min. Dilution : 1:50](https://www.genetex.com/upload/website/prouct_img/normal/GTX84216/GTX84216_2470_IHC-P_w_23061420_998.webp "IHC-P analysis of human bladder carcinoma tissue using GTX84216 LIN7B antibody [1C9]. Antigen retrieval : Heat-induced epitope retrieval by 10mM citrate buffer, pH6.0, 100oC for 10min. Dilution : 1:50")
![IHC-P analysis of human lymph node tissue using GTX84216 LIN7B antibody [1C9]. Antigen retrieval : Heat-induced epitope retrieval by 10mM citrate buffer, pH6.0, 100oC for 10min. Dilution : 1:50](https://www.genetex.com/upload/website/prouct_img/normal/GTX84216/GTX84216_2471_IHC-P_w_23061420_922.webp "IHC-P analysis of human lymph node tissue using GTX84216 LIN7B antibody [1C9]. Antigen retrieval : Heat-induced epitope retrieval by 10mM citrate buffer, pH6.0, 100oC for 10min. Dilution : 1:50")
![FACS analysis of HEK293T cells transfected with either LIN7B plasmid(Red) or empty vector control plasmid(Blue) using GTX84216 LIN7B antibody [1C9].](https://www.genetex.com/upload/website/prouct_img/normal/GTX84216/GTX84216_325_FACS_w_23061420_994.webp "FACS analysis of HEK293T cells transfected with either LIN7B plasmid(Red) or empty vector control plasmid(Blue) using GTX84216 LIN7B antibody [1C9].")
![WB analysis of HEK293T cells transfected with LIN7B plasmid (Right) or empty vector (Left) for 48 hrs using GTX84216 LIN7B antibody [1C9]. Loading : 5 ug per lane](https://www.genetex.com/upload/website/prouct_img/normal/GTX84216/GTX84216_4193_WB_w_23061420_850.webp "WB analysis of HEK293T cells transfected with LIN7B plasmid (Right) or empty vector (Left) for 48 hrs using GTX84216 LIN7B antibody [1C9]. Loading : 5 ug per lane")
![ICC/IF analysis of COS7 cells transiently transfected with LIN7B plasmid using GTX84216 LIN7B antibody [1C9].](https://www.genetex.com/upload/website/prouct_img/normal/GTX84216/GTX84216_985_ICCIF_w_23061420_979.webp "ICC/IF analysis of COS7 cells transiently transfected with LIN7B plasmid using GTX84216 LIN7B antibody [1C9].")
IHC-P analysis of human ovary adenocarcinoma tissue using GTX84216 LIN7B antibody [1C9]. Antigen retrieval : Heat-induced epitope retrieval by 10mM citrate buffer, pH6.0, 100oC for 10min. Dilution : 1:50
LIN7B antibody [1C9]
GTX84216
ApplicationsFlow Cytometry, ImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityHuman
TargetLIN7B
Overview
- SupplierGeneTex
- Product NameLIN7B antibody [1C9]
- Delivery Days Customer9
- Application Supplier NoteWB: 1:2000. ICC/IF: 1:100. IHC-P: 1:150. FACS: 1:100. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsFlow Cytometry, ImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
- CertificationResearch Use Only
- ClonalityMonoclonal
- Clone ID1C9
- Concentration0.58 mg/ml
- ConjugateUnconjugated
- Gene ID64130
- Target nameLIN7B
- Target descriptionlin-7 homolog B, crumbs cell polarity complex component
- Target synonymshLin7B; hVeli2; LIN-7B; MALS2; MALS-2; mammalian lin-seven protein 2; protein lin-7 homolog B; VELI2; veli-2; vertebrate lin-7 homolog 2
- HostMouse
- IsotypeIgG1
- Protein IDQ9HAP6
- Protein NameProtein lin-7 homolog B
- Scientific DescriptionPlays a role in establishing and maintaining the asymmetric distribution of channels and receptors at the plasma membrane of polarized cells. Forms membrane-associated multiprotein complexes that may regulate delivery and recycling of proteins to the correct membrane domains. The tripartite complex composed of LIN7 (LIN7A, LIN7B or LIN7C), CASK and APBA1 may have the potential to couple synaptic vesicle exocytosis to cell adhesion in brain. Ensures the proper localization of GRIN2B (subunit 2B of the NMDA receptor) to neuronal postsynaptic density and may function in localizing synaptic vesicles at synapses where it is recruited by beta-catenin and cadherin. Required to localize Kir2 channels, GABA transporter (SLC6A12) and EGFR/ERBB1, ERBB2, ERBB3 and ERBB4 to the basolateral membrane of epithelial cells. May increase the amplitude of ACCN3 acid-evoked currents by stabilizing the channel at the cell surface.
- ReactivityHuman
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203