Linifanib [796967-16-3]
T2514
Overview
- SupplierTargetMol Chemicals
- Product NameLinifanib [796967-16-3]
- Delivery Days Customer4
- CAS Number796967-16-3
- Category SupplierChemical
- CertificationResearch Use Only
- Chemical NameLinifanib
- Estimated Purity99.29%
- Molecular FormulaC21H18FN5O
- Molecular Weight375.4
- Scientific DescriptionLinifanib (AL-39324) (ABT-869) is a novel, potent ATP-competitive VEGFR/PDGFR inhibitor for KDR (IC50: 4 nM), CSF-1R (IC50: 3 nM), Flt-1/3 (IC50: 3/4 nM) and PDGFRbeta (IC50: 66 nM). Linifanib may exhibit potent antiproliferative and apoptotic effects on tumor cells whose proliferation is dependent on mutant kinases, such as FMS-related tyrosine kinase receptor-3 (FLT3).
- Shelf life instruction3 years
- SMILESCc1ccc(F)c(NC(=O)Nc2ccc(cc2)-c2cccc3[nH]nc(N)c23)c1
- Storage Instruction-20°C
- UNSPSC12352200
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