LITAF antibody [N1C3]

GeneTex

LITAF antibody [N1C3]

9

WB: 1:500-1:3000. IHC-P: 1:100-1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

ImmunoPrecipitation, Western Blot, ChIP Chromatin ImmunoPrecipitation, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin

Research Use Only

Polyclonal

1 mg/ml

Unconjugated

LITAF

lipopolysaccharide induced TNF factor

PIG7, SIMPLE, TP53I7, lipopolysaccharide-induced tumor necrosis factor-alpha factor, LPS-induced TNF-alpha factor, lipopolysaccharide-induced TNF-alpha factor, p53-induced gene 7 protein, small integral membrane protein of lysosome/late endosome, small integral membrane protein of the late endosome, tumor protein p53 inducible protein 7

Rabbit

IgG

Lipopolysaccharide-induced tumor necrosis factor-alpha factor

Lipopolysaccharide is a potent stimulator of monocytes and macrophages, causing secretion of tumor necrosis factor-alpha (TNF-alpha) and other inflammatory mediators. This gene encodes lipopolysaccharide-induced TNF-alpha factor, which is a DNA-binding protein and can mediate the TNF-alpha expression by direct binding to the promoter region of the TNF-alpha gene. The transcription of this gene is induced by tumor suppresor p53 and has been implicated in the p53-induced apoptotic pathway. Mutations in this gene cause Charcot-Marie-Tooth disease type 1C (CMT1C) and may be involved in the carcinogenesis of extramammary Pagets disease (EMPD). Multiple alternatively spliced transcript variants have been found for this gene. [provided by RefSeq]

-20°C or -80°C,2°C to 8°C

12352203