ICC/IF analysis of COS7 cells transiently transfected with Livin plasmid using GTX84822 Livin antibody [1B10].
Livin antibody [1B10]
GTX84822
ApplicationsFlow Cytometry, ImmunoFluorescence, Western Blot, ImmunoCytoChemistry
Product group Antibodies
ReactivityHuman
TargetBIRC7
Overview
- SupplierGeneTex
- Product NameLivin antibody [1B10]
- Delivery Days Customer9
- ApplicationsFlow Cytometry, ImmunoFluorescence, Western Blot, ImmunoCytoChemistry
- CertificationResearch Use Only
- ClonalityMonoclonal
- Clone ID1B10
- Concentration1 mg/ml
- ConjugateUnconjugated
- Gene ID79444
- Target nameBIRC7
- Target descriptionbaculoviral IAP repeat containing 7
- Target synonymsbaculoviral IAP repeat-containing protein 7; KIAP; kidney inhibitor of apoptosis protein; LIVIN; livin inhibitor of apoptosis; melanoma inhibitor of apoptosis protein; MLIAP; ML-IAP; RING finger protein 50; RING-type E3 ubiquitin transferase BIRC7; RNF50
- HostMouse
- IsotypeIgG1
- Scientific DescriptionProtects against apoptosis induced by TNF or by chemical agents such as adriamycin, etoposide or staurosporine. Suppression of apoptosis is mediated by activation of MAPK8/JNK1, and possibly also of MAPK9/JNK2. This activation depends on TAB1 and NR2C2/TAK1. In vitro, inhibits caspase-3 and proteolytic activation of pro-caspase-9. Isoform 1 blocks staurosporine-induced apoptosis. Isoform 2 blocks etoposide-induced apoptosis.
- ReactivityHuman
- Storage Instruction2°C to 8°C,-20°C or -80°C
- UNSPSC12352203