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IHC-P analysis of liver carcinoma tissue using GTX84823 Livin antibody [1D12]. Antigen retrieval : Heat-induced epitope retrieval by 10mM citrate buffer, pH6.0, 100oC for 10min. Dilution : 1:50
IHC-P analysis of liver carcinoma tissue using GTX84823 Livin antibody [1D12]. Antigen retrieval : Heat-induced epitope retrieval by 10mM citrate buffer, pH6.0, 100oC for 10min. Dilution : 1:50
IHC-P analysis of liver carcinoma tissue using GTX84823 Livin antibody [1D12]. Antigen retrieval : Heat-induced epitope retrieval by 10mM citrate buffer, pH6.0, 100oC for 10min. Dilution : 1:50

Livin antibody [1D12]

Research Use Only
GTX84823
GeneTex
ApplicationsFlow Cytometry, Western Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityHuman, Mouse
TargetBIRC7
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Overview

  • Supplier
    GeneTex
  • Product Name
    Livin antibody [1D12] - Overexpression Validated
  • Delivery Days Customer
    9
  • Application Supplier Note
    WB: 1:1000. IHC-P: 1:50. FACS: 1:100. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
  • Applications
    Flow Cytometry, Western Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
  • Certification
    Research Use Only
  • Clonality
    Monoclonal
  • Clone ID
    1D12
  • Concentration
    0.36 mg/ml
  • Conjugate
    Unconjugated
  • Formulation
    Liquid
  • Gene ID79444
  • Target name
    BIRC7
  • Target description
    baculoviral IAP repeat containing 7
  • Target synonyms
    baculoviral IAP repeat-containing protein 7; KIAP; kidney inhibitor of apoptosis protein; LIVIN; livin inhibitor of apoptosis; melanoma inhibitor of apoptosis protein; MLIAP; ML-IAP; RING finger protein 50; RING-type E3 ubiquitin transferase BIRC7; RNF50
  • Host
    Mouse
  • Isotype
    IgG1
  • Protein IDQ96CA5
  • Protein Name
    Baculoviral IAP repeat-containing protein 7
  • Scientific Description
    Protects against apoptosis induced by TNF or by chemical agents such as adriamycin, etoposide or staurosporine. Suppression of apoptosis is mediated by activation of MAPK8/JNK1, and possibly also of MAPK9/JNK2. This activation depends on TAB1 and NR2C2/TAK1. In vitro, inhibits caspase-3 and proteolytic activation of pro-caspase-9. Isoform 1 blocks staurosporine-induced apoptosis. Isoform 2 blocks etoposide-induced apoptosis.
  • Reactivity
    Human, Mouse
  • Storage Instruction
    -20°C or -80°C,2°C to 8°C
  • UNSPSC
    12352203