IHC-P analysis of liver carcinoma tissue using GTX84823 Livin antibody [1D12]. Antigen retrieval : Heat-induced epitope retrieval by 10mM citrate buffer, pH6.0, 100oC for 10min. Dilution : 1:50
![WB analysis of various samples using GTX84823 Livin antibody [1D12]. Loading : 10 ug per lane Dilution : 1:200](https://www.genetex.com/upload/website/prouct_img/normal/GTX84823/GTX84823_3573_WB_w_23061420_619.webp "WB analysis of various samples using GTX84823 Livin antibody [1D12]. Loading : 10 ug per lane Dilution : 1:200")
![WB analysis of human tissues (Lane 1-Testis ; Lane 2-Omentum ; Lane 3-Uterus ; Lane 4-Breast ; Lane 5-Brain ; Lane 6-Liver ; Lane 7-Ovary ; Lane 8-Thyroid gland ; Lane 9-colon ; Lane 10-spleen) using GTX84823 Livin antibody [1D12]. Loading : 10 ug per lane Dilution : 1:200](https://www.genetex.com/upload/website/prouct_img/normal/GTX84823/GTX84823_4263_WB_w_23061420_337.webp "WB analysis of human tissues (Lane 1-Testis ; Lane 2-Omentum ; Lane 3-Uterus ; Lane 4-Breast ; Lane 5-Brain ; Lane 6-Liver ; Lane 7-Ovary ; Lane 8-Thyroid gland ; Lane 9-colon ; Lane 10-spleen) using GTX84823 Livin antibody [1D12]. Loading : 10 ug per lane Dilution : 1:200")
![WB analysis of HEK293T cells transfected with Livin plasmid (Right) or empty vector (Left) for 48 hrs using GTX84823 Livin antibody [1D12]. Loading : 5 ug per lane](https://www.genetex.com/upload/website/prouct_img/normal/GTX84823/GTX84823_4647_WB_w_23061420_547.webp "WB analysis of HEK293T cells transfected with Livin plasmid (Right) or empty vector (Left) for 48 hrs using GTX84823 Livin antibody [1D12]. Loading : 5 ug per lane")
![FACS analysis of HeLa cells using GTX84823 Livin antibody [1D12]. Red : Primary antibody Blue : Negative control antibody](https://www.genetex.com/upload/website/prouct_img/normal/GTX84823/GTX84823_561_FACS_w_23061420_987.webp "FACS analysis of HeLa cells using GTX84823 Livin antibody [1D12]. Red : Primary antibody Blue : Negative control antibody")
![FACS analysis of Jurkat cells using GTX84823 Livin antibody [1D12]. Red : Primary antibody Blue : Negative control antibody](https://www.genetex.com/upload/website/prouct_img/normal/GTX84823/GTX84823_562_FACS_w_23061420_393.webp "FACS analysis of Jurkat cells using GTX84823 Livin antibody [1D12]. Red : Primary antibody Blue : Negative control antibody")
IHC-P analysis of liver carcinoma tissue using GTX84823 Livin antibody [1D12]. Antigen retrieval : Heat-induced epitope retrieval by 10mM citrate buffer, pH6.0, 100oC for 10min. Dilution : 1:50
Livin antibody [1D12] - Overexpression Validated
GTX84823
ApplicationsFlow Cytometry, Western Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityHuman, Mouse
TargetBIRC7
Overview
- SupplierGeneTex
- Product NameLivin antibody [1D12] - Overexpression Validated
- Delivery Days Customer9
- ApplicationsFlow Cytometry, Western Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
- CertificationResearch Use Only
- ClonalityMonoclonal
- Clone ID1D12
- Concentration0.36 mg/ml
- ConjugateUnconjugated
- Gene ID79444
- Target nameBIRC7
- Target descriptionbaculoviral IAP repeat containing 7
- Target synonymsbaculoviral IAP repeat-containing protein 7; KIAP; kidney inhibitor of apoptosis protein; LIVIN; livin inhibitor of apoptosis; melanoma inhibitor of apoptosis protein; MLIAP; ML-IAP; RING finger protein 50; RING-type E3 ubiquitin transferase BIRC7; RNF50
- HostMouse
- IsotypeIgG1
- Scientific DescriptionProtects against apoptosis induced by TNF or by chemical agents such as adriamycin, etoposide or staurosporine. Suppression of apoptosis is mediated by activation of MAPK8/JNK1, and possibly also of MAPK9/JNK2. This activation depends on TAB1 and NR2C2/TAK1. In vitro, inhibits caspase-3 and proteolytic activation of pro-caspase-9. Isoform 1 blocks staurosporine-induced apoptosis. Isoform 2 blocks etoposide-induced apoptosis.
- ReactivityHuman, Mouse
- Storage Instruction2°C to 8°C,-20°C or -80°C
- UNSPSC12352203