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ProductsBack/LKB1 antibody

LKB1 antibody

GTX130697

ApplicationsWestern Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin

Product group Antibodies

TargetSTK11

Overview

Supplier
GeneTex
Product Name
LKB1 antibody
Delivery Days Customer
9
Application Supplier Note
WB: 1:500-1:3000. IHC-P: 1:100-1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
Applications
Western Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Certification
Research Use Only
Clonality
Polyclonal
Concentration
1.6 mg/ml
Conjugate
Unconjugated
Gene ID6794
Target name
STK11
Target description
serine/threonine kinase 11
Target synonyms
LKB1, PJS, hLKB1, serine/threonine-protein kinase STK11, liver kinase B1, polarization-related protein LKB1, renal carcinoma antigen NY-REN-19, serine/threonine-protein kinase 11, serine/threonine-protein kinase LKB1
Host
Rabbit
Isotype
IgG
Protein IDQ15831
Protein Name
Serine/threonine-protein kinase STK11
Scientific Description
This gene, which encodes a member of the serine/threonine kinase family, regulates cell polarity and functions as a tumor suppressor. Mutations in this gene have been associated with Peutz-Jeghers syndrome, an autosomal dominant disorder characterized by the growth of polyps in the gastrointestinal tract, pigmented macules on the skin and mouth, and other neoplasms. Alternate transcriptional splice variants of this gene have been observed but have not been thoroughly characterized. [provided by RefSeq]
Storage Instruction
-20°C or -80°C,2°C to 8°C
UNSPSC
12352203

References

Jiang WP, Deng JS, Huang SS, et al. Sanghuangporus sanghuang Mycelium Prevents Paracetamol-Induced Hepatotoxicity through Regulating the MAPK/NF-κB, Keap1/Nrf2/HO-1, TLR4/PI3K/Akt, and CaMKKβ/LKB1/AMPK Pathways and Suppressing Oxidative Stress and Inflammation. Antioxidants (Basel). 2021,10(6). doi: 10.3390/antiox10060897
Read this paper
Tuo L, Xiang J, Pan X, et al. PCK1 negatively regulates cell cycle progression and hepatoma cell proliferation via the AMPK/p27(Kip1) axis. J Exp Clin Cancer Res. 2019,38(1):50. doi: 10.1186/s13046-019-1029-y
Read this paper

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