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LKB1 antibody

GTX130697
GeneTex
ApplicationsWestern Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
DownloadDatasheet
Product group Antibodies
TargetSTK11
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Overview

  • Supplier
    GeneTex
  • Product Name
    LKB1 antibody
  • Delivery Days Customer
    9
  • Application Supplier Note
    WB: 1:500-1:3000. IHC-P: 1:100-1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
  • Applications
    Western Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Concentration
    1.6 mg/ml
  • Conjugate
    Unconjugated
  • Gene ID6794
  • Target name
    STK11
  • Target description
    serine/threonine kinase 11
  • Target synonyms
    hLKB1; liver kinase B1; LKB1; PJS; polarization-related protein LKB1; renal carcinoma antigen NY-REN-19; serine/threonine-protein kinase 11; serine/threonine-protein kinase LKB1; serine/threonine-protein kinase STK11
  • Host
    Rabbit
  • Isotype
    IgG
  • Protein IDQ15831
  • Protein Name
    Serine/threonine-protein kinase STK11
  • Scientific Description
    This gene, which encodes a member of the serine/threonine kinase family, regulates cell polarity and functions as a tumor suppressor. Mutations in this gene have been associated with Peutz-Jeghers syndrome, an autosomal dominant disorder characterized by the growth of polyps in the gastrointestinal tract, pigmented macules on the skin and mouth, and other neoplasms. Alternate transcriptional splice variants of this gene have been observed but have not been thoroughly characterized. [provided by RefSeq]
  • Storage Instruction
    -20°C or -80°C,2°C to 8°C
  • UNSPSC
    12352203

References

  • Sanghuangporus sanghuang Mycelium Prevents Paracetamol-Induced Hepatotoxicity through Regulating the MAPK/NF-kappaB, Keap1/Nrf2/HO-1, TLR4/PI3K/Akt, and CaMKKbeta/LKB1/AMPK Pathways and Suppressing Oxidative Stress and Inflammation. Jiang WP et al., 2021 Jun 2, Antioxidants (Basel)
    Read more
  • PCK1 negatively regulates cell cycle progression and hepatoma cell proliferation via the AMPK/p27Kip1 axis. Tuo L et al., 2019 Feb 4, J Exp Clin Cancer Res
    Read more

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