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IHC-P analysis of human breast carcinoma tissue using GTX30765 LKB1 (phospho Ser428) antibody.
IHC-P analysis of human breast carcinoma tissue using GTX30765 LKB1 (phospho Ser428) antibody.
IHC-P analysis of human breast carcinoma tissue using GTX30765 LKB1 (phospho Ser428) antibody.

LKB1 (phospho Ser428) antibody

GTX30765
GeneTex
ApplicationsWestern Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityHuman, Monkey, Mouse
TargetSTK11
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Overview

  • Supplier
    GeneTex
  • Product Name
    LKB1 (phospho Ser428) antibody - Orthogonal Validated
  • Delivery Days Customer
    9
  • Application Supplier Note
    WB: 1:500 - 1:1000. IHC-P: 1:50 - 1:100. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
  • Applications
    Western Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Conjugate
    Unconjugated
  • Gene ID6794
  • Target name
    STK11
  • Target description
    serine/threonine kinase 11
  • Target synonyms
    hLKB1; liver kinase B1; LKB1; PJS; polarization-related protein LKB1; renal carcinoma antigen NY-REN-19; serine/threonine-protein kinase 11; serine/threonine-protein kinase LKB1; serine/threonine-protein kinase STK11
  • Host
    Rabbit
  • Isotype
    IgG
  • Protein IDQ15831
  • Protein Name
    Serine/threonine-protein kinase STK11
  • Scientific Description
    This gene, which encodes a member of the serine/threonine kinase family, regulates cell polarity and functions as a tumor suppressor. Mutations in this gene have been associated with Peutz-Jeghers syndrome, an autosomal dominant disorder characterized by the growth of polyps in the gastrointestinal tract, pigmented macules on the skin and mouth, and other neoplasms. Alternate transcriptional splice variants of this gene have been observed but have not been thoroughly characterized. [provided by RefSeq, Jul 2008]
  • Reactivity
    Human, Monkey, Mouse
  • Storage Instruction
    -20°C or -80°C,2°C to 8°C
  • UNSPSC
    12352203

References

  • Sanghuangporus sanghuang Mycelium Prevents Paracetamol-Induced Hepatotoxicity through Regulating the MAPK/NF-kappaB, Keap1/Nrf2/HO-1, TLR4/PI3K/Akt, and CaMKKbeta/LKB1/AMPK Pathways and Suppressing Oxidative Stress and Inflammation. Jiang WP et al., 2021 Jun 2, Antioxidants (Basel)
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  • LKB1/AMPKalpha signaling pathway and mitochondrial fission/fusion dynamics regulate apoptosis induced by 3-chlorpropane-1,2-diol in HEK293 cells. Jin C et al., 2021 Aug, Food Chem Toxicol
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  • Attenuation of Lipopolysaccharide-Induced Acute Lung Injury by Hispolon in Mice, Through Regulating the TLR4/PI3K/Akt/mTOR and Keap1/Nrf2/HO-1 Pathways, and Suppressing Oxidative Stress-Mediated ER Stress-Induced Apoptosis and Autophagy. Huang CY et al., 2020 Jun 10, Nutrients
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