LLY-283

MedChem Express

LLY-283 [2040291-27-6]

10

2040291-27-6

Research Use Only

99.22

C17H18N4O4

342.35

LLY-283 is a potent, selective and oral protein arginine methyltransferase 5 ( PRMT5 ) inhibitor, with an IC 50 of 22 nM and a K d of 6 nM for PRMT5:MEP50 complex, and shows antitumor activity.

O[C@H]1[C@@H](O[C@@]([C@@H](C2=CC=CC=C2)O)([H])[C@H]1O)N3C4=NC=NC(N)=C4C=C3

-20°C,2°C to 8°C

12352200