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LLY-283

M6312
AbMole BioScience
CAS Number2040291-27-6
Product group Chemicals
Molecular Weight342.35
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Overview

  • Supplier
    AbMole BioScience
  • Product Name
    LLY-283
  • Delivery Days Customer
    9
  • CAS Number
    2040291-27-6
  • Category Supplier
    Chemical
  • Certification
    Research Use Only
  • Molecular Formula
    C17H18N4O4
  • Molecular Weight
    342.35
  • Scientific Description
    LLY-283 is the potent and selective SAM-competitive chemical probe for PRMT5. It inhibits PRMT5 enzyme activity with IC50 of 20 nM for methylation of an H4R3 derived peptide substrate, and shows greater than 100-fold selectivity over other histone methyltransferases and non-epigenetic targets.
  • SMILES
    NC1=NC=NC2=C1C=C[N]2C3OC(C(O)C3O)C(O)C4=CC=CC=C4
  • UNSPSC
    12352200