LLY-283
M6312
CAS Number2040291-27-6
Product group Chemicals
Molecular Weight342.35
Overview
- SupplierAbMole BioScience
- Product NameLLY-283
- Delivery Days Customer9
- CAS Number2040291-27-6
- Category SupplierChemical
- Molecular FormulaC17H18N4O4
- Molecular Weight342.35
- Scientific DescriptionLLY-283 is the potent and selective SAM-competitive chemical probe for PRMT5. It inhibits PRMT5 enzyme activity with IC50 of 20 nM for methylation of an H4R3 derived peptide substrate, and shows greater than 100-fold selectivity over other histone methyltransferases and non-epigenetic targets.
- SMILESNC1=NC=NC2=C1C=C[N]2C3OC(C(O)C3O)C(O)C4=CC=CC=C4
- UNSPSC12352200