Loricrin antibody [N1], N-term
GTX116013
ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityHuman
TargetLORICRIN
Overview
- SupplierGeneTex
- Product NameLoricrin antibody [N1], N-term
- Delivery Days Customer9
- Application Supplier NoteWB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
- CertificationResearch Use Only
- ClonalityPolyclonal
- Concentration0.24 mg/ml
- ConjugateUnconjugated
- Gene ID4014
- Target nameLORICRIN
- Target descriptionloricrin cornified envelope precursor protein
- Target synonymsLOR, loricrin
- HostRabbit
- IsotypeIgG
- Protein IDP23490
- Protein NameLoricrin
- Scientific DescriptionThis gene encodes loricrin, a major protein component of the cornified cell envelope found in terminally differentiated epidermal cells. Mutations in this gene are associated with Vohwinkels syndrome and progressive symmetric erythrokeratoderma, both inherited skin diseases. [provided by RefSeq]
- ReactivityHuman
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203
References
- Oh JS, Lee SJ, Choung SY. Lithospermum erythrorhizon Alleviates Atopic Dermatitis-like Skin Lesions by Restoring Immune Balance and Skin Barrier Function in 2.4-Dinitrochlorobenzene-Induced NC/Nga Mice. Nutrients. 2021,13(9). doi: 10.3390/nu13093209Read this paper
- Roy RR, Shimada K, Murakami S, et al. Contribution of transglutaminases and their substrate proteins to the formation of cornified cell envelope in oral mucosal epithelium. Eur J Oral Sci. 2021,129(1):e12760. doi: 10.1111/eos.12760Read this paper
- Kim SH, Seong GS, Choung SY. Fermented Morinda citrifolia (Noni) Alleviates DNCB-Induced Atopic Dermatitis in NC/Nga Mice through Modulating Immune Balance and Skin Barrier Function. Nutrients. 2020,12(1). doi: 10.3390/nu12010249Read this paper
- Wang C, Zong J, Li Y, et al. MiR-744-3p regulates keratinocyte proliferation and differentiation via targeting KLLN in psoriasis. Exp Dermatol. 2019,28(3):283-291. doi: 10.1111/exd.13888Read this paper
- Wang S, Qiu L, Meng X, et al. Knock-down of filaggrin influences the mitogen-activated protein kinases signaling pathway in normal human epidermal keratinocytes. Med Sci (Paris). 2018,34 Focus issue F1:94-98. doi: 10.1051/medsci/201834f116Read this paper
- Shimada K, Ochiai T, Hasegawa H. Ectopic transglutaminase 1 and 3 expression accelerating keratinization in oral lichen planus. J Int Med Res. 2018,46(11):4722-4730. doi: 10.1177/0300060518798261Read this paper
- Qian L, Xu F, Wang X, et al. LncRNA expression profile of ΔNp63α in cervical squamous cancers and its suppressive effects on LIF expression. Cytokine. 2017,96:114-122. doi: 10.1016/j.cyto.2017.04.001Read this paper
- Wang T, Zhao N, Long S, et al. Downregulation of miR-205 in migrating epithelial tongue facilitates skin wound re-epithelialization by derepressing ITGA5. Biochim Biophys Acta. 2016,1862(8):1443-52. doi: 10.1016/j.bbadis.2016.05.004Read this paper
- Dang NN, Pang SG, Song HY, et al. Filaggrin silencing by shRNA directly impairs the skin barrier function of normal human epidermal keratinocytes and then induces an immune response. Braz J Med Biol Res. 2015,48(1):39-45.Read this paper
Datasheet
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