Lorlatinib (PF-06463922)
M3975
CAS Number1454846-35-5
Product group Chemicals
Estimated Purity1
Molecular Weight406.41
Overview
- SupplierAbMole BioScience
- Product NameLorlatinib (PF-06463922)
- Delivery Days Customer9
- CAS Number1454846-35-5
- Category SupplierChemical
- CertificationResearch Use Only
- Estimated Purity1
- Molecular FormulaC21H19FN6O2
- Molecular Weight406.41
- Scientific DescriptionLorlatinib (PF-06463922) is an oral active, selective, brain osmotic and ATP-competitive ROS1/ALK inhibitor. The Ki of Lorlatinib for ROS1, wild-type ALK and ALK(L1196M) were <0.025 nM, <0.07 nM and 0.7 nM, respectively. Lorlatinib has anticancer activity.
- SMILESCC1OC2=C(N)N=CC(=C2)C3=C(C#N)[N](C)N=C3CN(C)C(=O)C4=C1C=C(F)C=C4
- UNSPSC12352200
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