Lovastatin [75330-75-5]

Chemodex

Lovastatin [75330-75-5]

10

75330-75-5

Research Use Only

>98%

Warning

C24H36O5

404.54

Chemical. CAS: 75330-75-5. Formula: C24H36O5. MW: 404.54. Lovastatin is an inhibitor of 3-hydroxy-3-methylglutaryl-coenzyme A reductase (HMG-CoA reductase), an enzyme that catalyzes the conversion of HMG-CoA to mevalonate. Lovastatin is a prodrug, which is hydrolyzed in vivo to the active beta-hydroxy acid open ring form. Mevalonate is a required building block for cholesterol biosynthesis and lovastatin interferes with its production by acting as a reversible competitive inhibitor for HMG-CoA. Lovastatin is an effective anti-hypercholesterolemic agent widely used as a lipid-lowering drug. In addition to lowering blood lipid levels, Lovastatin also has been shown to have anticancer, neuroprotective, anti-inflammatory, antiviral and antibacterial properties. - Lovastatin is an inhibitor of 3-hydroxy-3-methylglutaryl-coenzyme A reductase (HMG-CoA reductase), an enzyme that catalyzes the conversion of HMG-CoA to mevalonate. Lovastatin is a prodrug, which is hydrolyzed in vivo to the active beta-hydroxy acid open ring form. Mevalonate is a required building block for cholesterol biosynthesis and lovastatin interferes with its production by acting as a reversible competitive inhibitor for HMG-CoA. Lovastatin is an effective anti-hypercholesterolemic agent widely used as a lipid-lowering drug. In addition to lowering blood lipid levels, Lovastatin also has been shown to have anticancer, neuroprotective, anti-inflammatory, antiviral and antibacterial properties.

C[C@H]1C=CC2=C[C@H](C)C[C@H](OC([C@@H](C)CC)=O)[C@]2([H])[C@H]1CC[C@H]3OC(C[C@H](O)C3)=O

2°C to 8°C,RT

12352200