LV-320

MedChem Express

LV-320 [2449093-46-1]

10

2449093-46-1

Research Use Only

95.0

C29H26ClNO2S2

520.11

LV-320 is a potent and uncompetitive ATG4B inhibitor with an IC50 of 24.5?microM and a Kd of 16?microM. LV-320 inhibits ATG4B enzymatic activity, blocks autophagic flux in cells, and is stable, non-toxic and active in vivo[1].

ClC1=CC2=NC=CC(/C=C/C3=CC=C(C(SCCC(O)=O)SCCC4=CC=CC=C4)C=C3)=C2C=C1

-20°C,2°C to 8°C

12352200