LV-320 [2449093-46-1]

TargetMol Chemicals

LV-320 [2449093-46-1]

10

2449093-46-1

Chemical

Research Use Only

LV-320

C29H26ClNO2S2

520.11

LV-320 is a potent, uncompetitive ATG4B inhibitor with an IC50 of 24.5 microM and a Kd of 16 microM. LV-320 inhibits ATG4B enzymatic activity, blocks autophagic flux in cells, and is stable, non-toxic, and active in vivo. These findings suggest that LV-320 will serve as a relevant chemical tool to study the various roles of ATG4B in cancer and other contexts [1].

3 years

OC(=O)CCSC(SCCc1ccccc1)c1ccc(\C=C\c2ccnc3cc(Cl)ccc23)cc1

-20°C

12352200